Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis.

Front Cell Neurosci · 2020 · PMC7235295 · PMID 32477070

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did not reach statistical significanceno p-value reported

Likewise, miR-129-5p increased in both WT-TDP43-eGFP-His and ΔNLS-TDP43-eGFP-His cell lines but did not reach statistical significance ( Figures 4B,C ). miRNA pathway analysis of the 65 miRNAs using mirPath v.3 (Vlachos et al., 2015 ) further revealed several predicted gene targets and associated KEGG pathways that offered insight into the relevance of the identified cyTDP43-interacting miRNAs.

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