Alterations in the nigrostriatal system following conditional inactivation of α-synuclein in neurons of adult and aging mice.

This downregulation in a region where cell bodies of SNpc dopaminergic neurons are located is consistent with a trend for reduction of the protein level in the dorsal striatum, although the difference revealed by quantitation of Western blot data from available samples did not reach statistical significance mainly because of inconsistent low ALDH1a1 level in one of the control samples ( Fig. 7 E and F).

also in 111,027 other papers