β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1.

In the presence of MTA, the in vitro effects of training, which were assessed by IL-6 and TNF-α production, were significantly reduced and a similar trend was observed with ITF2357, although it did not reach statistical significance (p = 0.07) ( Figure 1 F).

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