Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: A systematic review and meta-analysis.

PLoS Med · 2020 · PMC7244100 · PMID 32442232

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0.0900

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did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

In two studies including 221 women [ 38 , 55 ], there was a nonsignificant decrease in macrosomia in metformin-exposed compared to glyburide-exposed neonates, although this did not reach statistical significance (OR 0.32, 95% CI 0.08 to 1.19, I 2 = 0%, p = 0.09) ( Fig 4C ).

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