The 5-year change in the level of other MMPs did not reach statistical significance compared to baseline but some, such as MMP-2 and MMP-10 when compared to early time-points following initiation of CPAP treatment also significantly increased by the end of the study (Fig. 2 ).
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Effect of 5-year continuous positive airway pressure treatment on MMPs and TIMPs: implications for OSA comorbidities.
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