In line with mass spectrometry data, western blot analysis showed a significant increase in SOX9 expression levels in RTT lines when compared to iCTR ( p = 0.0057, unpaired t test), and a decrease in SOX2 expression in RTT lines at D22, although this did not reach statistical significance ( p = 0.07, unpaired t test).
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Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors.
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