Lifespan of long-lived growth hormone receptor knockout mice was not normalized by housing at 30°C since weaning.

The results from the current study showed that GHRKO mice chronically housed at 30°C had higher body temperature than the animals housed at standard room temperature (23°C) (Figure 3 a), while their VO 2 (Figure 3 b,c) and heat production (Figure 3 d,e) had decreased (although the decrease did not reach statistical significance).

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