Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry.

Pharmacogenomics J · 2020 · PMC7260079 · PMID 31806883

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approached significanceno p-value reported

With analysis of SNV-thiazide interactions on LDL, four SNVs on chromosome 17 in KIAA0753 showed suggestive association in trans-ancestry (most significant rs2304976, P = 1.31×10 −7 , MANTRA log 10 [BF] = 5.34) although neither SNV approached significance in separate EA and AA analyses.

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