showed a trendP = 0.064
Sensitivity analysis Separate multivariable analyses for cohort I (age ≥75 years) and cohort III (age ≥50 years) demonstrated no significant association between cholecystectomy and MS in cohort I (OR 1.146, 95% CI 0.547–2.402, P = 0.718); however, the association between cholecystectomy and MS in cohort III showed a trend toward association (OR 2.029, 95% CI 0.958–4.295, P = 0.064).