Concordance between TP53 alterations in blood and tissue: impact of time interval, biopsy site, cancer type and circulating tumor DNA burden.

Mol Oncol · 2020 · PMC7266274 · PMID 32187847

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

showed a trendP = 0.09so close (0.05 < p ≤ 0.1)

Longer time intervals between blood and tissue sampling reduced the positive predictive value ( P = 0.002) and showed a trend toward reduction of the specificity ( P = 0.09).

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