We observed a pattern of cell death across ages in both male ( Figure 3B ) and female ( Figure 3C ) control mice that replicated the previously described pattern of reduced cell death across age ( Sun et al., 2004 ) and was slightly reminiscent of the previously described inverted U pattern of cell death across age ( Ben Abdallah et al., 2010 ), although the rate of pyknosis was very similar between 4 and 8 weeks with only slight increases in males and females that did not reach statistical significance.
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