Nicotinamide <i>N</i>-Methyltransferase: Genomic Connection to Disease.

Across the 7 SNPs, only 1 haplotype was strongly associated with the disease (A G G C T C T, in the order of SNPs listed above), again only in females ( P = .0015), and 1 was on the borderline of significance (G G G C T C T; P = .05).

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56 These authors subjected overweight men to a combination of food deprivation and vigorous exercise (−5000 kcal/d energy balance) for 4 days, causing a highly significant reduction in white cell fat.

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No association of any single NNMT SNP was found, although the minor base of rs3819100 approached significance.

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