Analysis of a Real-World Cohort of Metastatic Breast Cancer Patients Shows Circulating Tumor Cell Clusters (CTC-clusters) as Predictors of Patient Outcomes.

Changes in CTC-cluster counts from baseline to follow up were not able to predict patient outcome in terms of PFS and OS, however, for patients in the high risk group, there was a clear trend towards a shorter OS ( P log-rank = 0.07) and increased risk of death, with a HR of 2.96 (95% CI 0.83–10.5; p = 0.09) ( Figure 4 , Table 4 ). 2.6.

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