Barely Significant
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Combination therapy with dendritic cell vaccine and programmed death ligand 1 immune checkpoint inhibitor for hepatocellular carcinoma in an orthotopic mouse model.

Ther Adv Med Oncol · 2020 · PMC7288802 · PMID 32565925

Europe PMCDOI
1
hedged sentence
0.4151
closest p · 8.3× alpha
0.4151
boldest claim

The sentences

did not reach statistical significancep = 0.4151not close (p > 0.1)
The significant difference in tumor volume between single and combination treatment was shown in the mDC combined with high dosage rather than low dosage of anti-PD-L1, suggesting that the mDC combined with anti-PD-L1 treatment decreased tumor volume of mice in a dose-dependent manner; however, the difference between the mDC + anti-PD-L1 (100 μg/dose) and mDC + anti-PD-L1 (200 μg/dose) treatment did not reach statistical significance ( p = 0.4151).

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