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An Elvitegravir Nanoformulation Crosses the Blood-Brain Barrier and Suppresses HIV-1 Replication in Microglia.

Viruses · 2020 · PMC7290679 · PMID 32443728

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showed a trendno p-value reported
PLGA-EVG NPs also showed a trend of decreasing viral load in the CNS in the humanized HIVE mice model, as compared with the EVG native drug.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.