Proenkephalin Predicts Organ Failure, Renal Replacement Therapy, and Mortality in Patients With Sepsis.

Ann Lab Med · 2020 · PMC7295958 · PMID 32539302

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an increasing trendno p-value reported

PENK quartiles were also associated with an increasing trend in the number of organ failures ( Table 2 ); this implies that the PENK level might reflect sepsis-induced organ failure simply and objectively and has the clinical potential to substitute for or augment SOFA scores.

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did not reach statistical significanceno p-value reported

Regarding SOFA renal subscores, although RRT requirements were significantly different according to each subscore, the number of organ failures did not reach statistical significance.

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