Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value.

Front Neurosci · 2020 · PMC7300175 · PMID 32595447

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a clear trendno p-value reported

In SOD1 low expressor mice, also presymptomatic animals already showed a clear trend toward increased NF-L levels that would prevent the use of tissue from presymptomatic SOD1 low expressor mice as baseline for NF-L measurement but reflects the results observed in human AD tissue.

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