The parent drugs chloroquine and hydroxychloroquine do not inhibit human CYP3A activity in vitro.

Eur J Clin Pharmacol · 2020 · PMC7301348 · PMID 32556540

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showed a trendno p-value reported

At higher midazolam concentrations, enzyme activity showed a trend to increase with higher concentrations of both chloroquine and hydroxychloroquine.

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