High fat diet worsens Alzheimer's disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flow.

In the balance beam test of sensory-motor function, we did not observe a deficit in APP/PS1 mice on a normal diet and saw a weak trend toward impairment in WT mice on the Hfd, but we did find a strong impairment with the Hfd in the APP/PS1 mice.

also in 1,404 other papers

The WT-Hfd group also showed a trend toward impaired performance on the OR task.

also in 53,322 other papers