Hemophilia A Inhibitor Subjects Show Unique PBMC Gene Expression Profiles That Include Up-Regulated Innate Immune Modulators.

Front Immunol · 2020 · PMC7303277 · PMID 32595650

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did not reach statistical significanceno p-value reported

Intracellular staining experiments demonstrated increased IL-32 expression following FVIII stimulation in PBMCs, CD4 + , and CD14 + cells from two of three individual HA (current inhibitor) subjects, but the average increase for these three subjects did not reach statistical significance ( Supplemental Figure 1 ).

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