Impact of the first-line treatment shift from dihydroartemisinin/piperaquine to artesunate/mefloquine on Plasmodium vivax drug susceptibility in Cambodia.

J Antimicrob Chemother · 2020 · PMC7303819 · PMID 32211790

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did not reach statistical significanceno p-value reported

The double T958M-F1076L mutant parasites had a median IC 50 of 4.4 nM (IQR 2.0–4.9), intermediate between single and triple mutants, although the differences did not reach statistical significance.

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