EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.

Oncogene · 2020 · PMC7305988 · PMID 32457468

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trending towards significanceno p-value reported

We found a positive correlation between EZH2 expression and cisplatin IC50 trending towards significance, suggesting that as EZH2 expression increases, SCLC cells become more resistant to cisplatin.

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