In agreement with that, many of these genes were significantly down-regulated at the protein and/or mRNA level in YAP KO cells (for example, CYR61 , TEAD4 , CDK6 , and several centromere genes; Dataset S2 ) or showed a trend toward lowered transcript levels in the RNA-seq data.
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Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta.
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