Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.

J Alzheimers Dis · 2020 · PMC7306898 · PMID 32280089

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near-significantno p-value reported

Compared to patients with subthreshold plasma concentrations, patients with plasma C max,ss above the 0.346 ng/ml threshold at the 8 mg/day dose have significantly better outcomes on FAQ, Modified-CGIC, WBV, LVV, and FTV, and near-significant differences on ACE-R and UPDRS.

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