Relapse Patterns in NMOSD: Evidence for Earlier Occurrence of Optic Neuritis and Possible Seasonal Variation.

Front Neurol · 2020 · PMC7308484 · PMID 32612571

Europe PMC DOI

hedged sentences

0.0650

closest p · 1.3× alpha

0.0820

boldest claim

The sentences

showed a trendP = 0.065so close (0.05 < p ≤ 0.1)

Analysis by month of relapse in NMOSD showed a trend toward reduced risk of relapse in February to April compared to a peak in November to January ( P = 0.065).

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marginal significanceP = 0.082so close (0.05 < p ≤ 0.1)

The auto regressive integrated moving average analysis indicated a marginal significance of month on number of relapses per month with coefficient = 0.531 C95% CI − 0.678 – 1.13, P = 0.082) and adjusted coefficient = 3.677 (95% CI 2.034–5.320, P < 0.001).

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