Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function.

Another study in women with PCOS treated with 850 mg of metformin from the first trimester to term, shows that, at 8 years of age, children exposed prenatally to metformin exhibits higher glucose levels and a strong trend towards elevated systolic blood pressure and a lower LDL cholesterol level ( Ro et al., 2012 ).

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