Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy.

Front Pharmacol · 2020 · PMC7311751 · PMID 32625092

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showed a trendno p-value reported

A subsequent meta-analysis, including about 350 Caucasian patients with LARC and evaluating the role of EGFR rs2227983 and rs45608036 on the response to chemoradiation therapy, showed a trend for a detrimental effect on the response to treatment of the EGFR shorter (S) alleles ( Zhao et al., 2015 ).

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