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Association between uric acid levels and cardio-renal outcomes and death in patients with type 2 diabetes: A subanalysis of EMPA-REG OUTCOME.

Diabetes Obes Metab · 2020 · PMC7317186 · PMID 32030863

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The risk of ACM and stroke increased with each corresponding rise in serum uric acid level of 59 μmol/L (HR 1.06, 95% CI, 1.03–1.09 and HR 1.19, 95% CI, 1.08–1.31, respectively); for CHD, there was a trend towards a higher risk of CHD with a 59‐μmol/L increase in serum uric acid, although this did not reach statistical significance. 9 The results of these recent meta‐analyses lend further weight to the association between serum uric acid levels and risk of CV and kidney disease, including in patients with type 2 diabetes.

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