The effect of PER on amplitude did not reach statistical significance (19.87 ± 4.1 to 10.83 ± 2.92 pA; P = 0.06), but the charge transfer was significantly reduced (Fig. 2J ; 341 ± 1622 vs. 169 ± 115 fC, n = 6, P = 0.03).
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Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition.
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