Inflammatory bowel disease in Africa: what is the current state of knowledge?

38 In a case–control study in Algeria, the observed frequency of NOD2 mutant alleles was similar to that reported in European populations and a higher proportion of Crohn’s patients were carriers of at least one mutant allele in any variant (18.6% Crohn’s patients vs 10.2% controls); however, this association did not reach statistical significance.

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