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Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes.

BMC Med Genomics · 2020 · PMC7325014 · PMID 32600345

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By Mendelian randomization, we identified a 27% increased risk of eczema for each 1 standard deviation increase in eosinophil percentage by inverse variance weighted method (95% confidence interval = 9–48%, P = 0.002), although the association did not reach statistical significance for weighted median or MR-Egger methods (Additional file 1 : Tables S19-S20).

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