near-significantp = 0.0505
There was also a near-significant decrease in VEGF levels in placentas from treated animals compared to those from control animals (34.78 ± 2.36 pg/mg vs. 41.99 ± 2.47 pg/mg, respectively; p = 0.0505) (Fig. 4b ) and a significant decrease in plasma free VEGF, which is VEGF unbound by sFlt-1 (1174 ± 38.45 pg/mL vs. 1492 ± 62.25 pg/mL, respectively; p = 0.0006) (Fig. 4c ).