Barely Significant
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Improvement of Pain and Function After Use of a Topical Pain Relieving Patch: Results of the RELIEF Study.

J Pain Res · 2020 · PMC7326193 · PMID 32617016

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a clear trendno p-value reported
Although a minority of patients reported using opioids, anticonvulsants, and muscle relaxants, there was a clear trend in the treatment group toward a decrease in these agents as compared to baseline.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.