Likewise, the antioxidant response does not show the increment observed in normoxic conditions, even though FA BM-MNCs show a negative trend, but not significant, of the level of antioxidant capacity and scavengers with respect to HD BM-MNCs ( Fig. 6 ).
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The passage from bone marrow niche to bloodstream triggers the metabolic impairment in Fanconi Anemia mononuclear cells.
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