Perturbed Mitochondrial Dynamics Is a Novel Feature of Colitis That Can Be Targeted to Lessen Disease.

Cell Mol Gastroenterol Hepatol · 2020 · PMC7327843 · PMID 32298841

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Inhibitors of Mitochondrial Fission Do Not Affect Dextran Sodium Sulfate or Lipopolysaccharide-Evoked Cytokine Production Epithelia treated with DSS showed a trend toward decreased keratinocyte chemoattractant production, whereas macrophages displayed only small increases in TNFα and IL10 on in vitro exposure to DSS.

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