In the forward and reverse learning trials, no statistically significant learning deficits were observed in the Vehicle-treated PS19 mice although the Vehicle-treated PS19 mice showed a trend towards increased escape latency the hidden platform in the reverse learning trial compared to AZD0530-treated PS19 mice and both WT groups (Supplementary Fig.
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Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy.
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