The colonic mucosa-associated microbiome in SIV infection: shift towards Bacteroidetes coincides with mucosal CD4⁺ T cell depletion and enterocyte damage.

Although correlations did not reach statistical significance in this small group of animals, where the minimum r -value of 0.886 is required to yield P -values of ≤ 0.05, these trends indicate that the initial SIV infection-associated depletion of mucosal T helper cells might influence the proportion of Bacteroidetes within the mucosa-associated microbiome.

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