Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection.

In meta-analysis, only the HLA-DQB1 variant showed a nominally significant independent replication for a variant in HLA-DQB1 (OR = 15.6, P = 0.015, positive predictive value = 35.1), while a novel variant in rs149104283, an intronic transcript of SLCO1B3 and SLCO1B7 , was associated with CIAG (OR = 4.32, P = 1.79 × 10 −8 ) (Legge et al. 2017 ), but was not replicated in a Japanese sample (Saito et al. 2017 ).

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