Quantitative Hybrid Cardiac [<sup>18</sup>F]FDG-PET-MRI Images for Assessment of Cardiac Repair by Preconditioned Cardiosphere-Derived Cells.

Mol Ther Methods Clin Dev · 2020 · PMC7341058 · PMID 32671138

Europe PMC DOI

hedged sentences

0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

failed to reach statistical significancep = 0.13not close (p > 0.1)

LV EF was improved compared to untreated AMI but failed to reach statistical significance (p = 0.13; CDC: 43.5% ± 7.1%, apoCDC: 45.8 ± 8.6, and untreated AMI: 39.8% ± 6.1%). 3-day LV end-diastolic volume (EDV) and end-systolic volume (ESV) were similar in all groups ( Figure S6 ), but they were lower at the 1-month follow-up in both CDC and apoCDC groups, as compared to untreated AMI group.

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failed to reach significanceno p-value reported

The reduction of the LV EF after 1 month was mitigated by cell treatment, but differences between CDC/apoCDC and untreated animals failed to reach significance.

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a nonsignificant trendno p-value reported

We found a similar pattern in nontreated infarcted pig hearts 1 month after MI compared to the myocardium of control animals and a nonsignificant trend toward increased miR-1 levels in infarcted myocardium after treatment with CDCs or apoCDCs.

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