The association with participant mortality in e2e3 trended in the protective direction but did not reach statistical significance, likely due to the limited follow-up thus far. e2e2 had much lower apolipoprotein B, LDL cholesterol, total cholesterol, and lipoprotein A, and reticulocyte counts but higher apolipoprotein A1 and markedly higher triglycerides and RDW levels than e3e3.
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<i>ApoE</i> e2 and aging-related outcomes in 379,000 UK Biobank participants.
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