The Dynamic Scleral Extracellular Matrix Alterations in Chronic Ocular Hypertension Model of Rats.

Front Physiol · 2020 · PMC7349004 · PMID 32719611

Europe PMC DOI

hedged sentences

0.0780

closest p · 1.6× alpha

0.0780

boldest claim

The sentences

borderline significanceP = 0.078so close (0.05 < p ≤ 0.1)

Western blot analysis revealed a decreased COL1 with borderline significance (0.73 fold change, P = 0.078) and increased elastin and MMP2 (elastin: 1.70 fold change, P = 0.003; MMP2: 1.89 fold change, P < 0.001) when compared to the left eyes ( Figures 3D,F ).

also in 7,017 other papers

did not reach statistical significanceno p-value reported

ECM Alterations of the Sclera Under Chronic Elevated IOP for 2 Weeks At 2 weeks, immunohistochemical staining showed that the immunoreactivity of COL1 in the hypertensive right eyes (OD) seemed lower than that in the contralateral left eyes (OS), but the semi-quantitative analysis of the immunofluorescent density did not reach statistical significance ( Figure 3A ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.