In a large Canadian cohort of 132,256 births, maternal exposure to NO was associated with increased risk of development of autism spectrum disorders in children (OR 1.07, 95% CI 1.01–1.13 per IQR increase), whereas associations were less pronounced (or only showed a trend) for PM2.5 (OR 1.04, 95% CI 0.98–1.10) and NO 2 (OR 1.06, 95% CI 0.99–1.12) [ 97 ].
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Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress.
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