Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats.

At six weeks, there was a smaller difference between the two groups, which did not reach statistical significance ( Figure 1 ).

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Treatment with LV-UCP2 delayed the onset of stroke by about 12–14 days with respect to rats treated with the empty vector; the difference between the two groups of rats was highly significant ( Figure 2 ). 2.4.

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