Hot Spot TERT Promoter Mutations Are Rare in Sporadic Pancreatic Neuroendocrine Neoplasms and Associated with Telomere Length and Epigenetic Expression Patterns.

Cancers (Basel) · 2020 · PMC7352723 · PMID 32575418

Europe PMC DOI

hedged sentences

0.0860

closest p · 1.7× alpha

0.1490

boldest claim

The sentences

marginally significantp = 0.086so close (0.05 < p ≤ 0.1)

Binary category analyses indicated a marginally significant relationship between TPM status and longer telomeres ( p = 0.086), and changes in expression of miR449a ( p = 0.157), HDAC4 ( p = 0.146) and HDAC9 ( p = 0.149).

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showed a trendp = 0.149not close (p > 0.1)

The five TPM cases showed a trend ( p = 0.149) for decreased/absent HDAC9 expression in the nucleus of pNEN cells.

also in 53,322 other papers

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