Subcutaneous Administration of Apolipoprotein J-Derived Mimetic Peptide d-[113-122]apoJ Improves LDL and HDL Function and Prevents Atherosclerosis in LDLR-KO Mice.

Probably, the relatively weak association between LDL electronegativity and atherosclerosis was due to the small sample size ( n = 4 in each group), but a clear trend of statistical significance was observed.

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We found statistically significant correlations between the area of atherosclerotic lesions and the hepatic expression of Ccl2 , Tnfα , and Cd68 , and a positive trend with Cd36 .

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