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Metagenomic Characterization of Gut Microbiota of Carriers of Extended-Spectrum Beta-Lactamase or Carbapenemase-Producing Enterobacteriaceae Following Treatment with Oral Antibiotics and Fecal Microbiota Transplantation: Results from a Multicenter Randomized Trial.

Microorganisms · 2020 · PMC7357103 · PMID 32585945

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While the intervention effect did not reach statistical significance (odd ratios for decolonization was 1.7 [95% CI 0.4–6.4]), possibly because of the failure to achieve the planned sample size, the loss of ESBL-E/CPE carriage detectable by culture was more frequent in FMT-treated participants than in the treatment-naïve control group.

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