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Statistical Issues and Lessons Learned From COVID-19 Clinical Trials With Lopinavir-Ritonavir and Remdesivir.

JMIR Public Health Surveill · 2020 · PMC7357691 · PMID 32589146

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The sample size was increased from 160 to 199 since the result with the enrolled 160 patients did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.