Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons.

Scintillation counts showed a trend for increased 3 H-glucose signal in IRβ-expressing cells (Student’s t -test; p = 0.120), which exhibited ∼30% more uptake than control cells ( Figure 1E ).

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