Differential Expression of Ormdl Genes in the Islets of Mice and Humans with Obesity.

iScience · 2020 · PMC7358727 · PMID 32659722

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All ORMDL genes showed a trend toward diminished mRNA expression in islets isolated from overweight/obese humans as compared with lean (as quantified by cycle threshold compared with β-actin), with the cycles necessary to amplify ORMDL3 PCR product being significantly reduced (approximately 3.5 cycles, or 11-fold) ( Figures 1 A–1C).

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