Mcl-1 protects eosinophils from apoptosis and exacerbates allergic airway inflammation.

However, hMcl-1 mice had an exacerbated allergic response to OVA with increased BALF cellularity, eosinophil numbers, airway mucus production and BALF total protein ( figure 1B–F ), with an increase in the proportion of interstitial eosinophils that did not reach statistical significance ( figure 1G ).

also in 111,027 other papers